The Science Behind CBD

What is CBD?

Cannabidiol (CBD) is a safe, non-psychoactive, naturally occurring compound in plants (a phytocannabinoid) which is most prominently found in hemp. CBD is one of the over 100 cannabinoids found in cannabis plants that has shown early promise in delivering a myriad of benefits for both pets and people. Research so far, much of which has been sponsored by the US government, has shown potential for assisting with a wide range of conditions.

Extraction Process

We utilize ethanol extraction to extract out all of the key compounds from our hemp plants. We decided on ethanol extraction after exploring many different options because it’s currently the best method for preserving cannabinoids, terpenes, bioflavonoids, and other beneficial compounds found in hemp safely and free of solvents at the end of the process. Utilizing ethanol as a solvent for extraction has been extensively researched by the scientific community and is regarded as one of the safest and preferred methods for herbal extraction, including for pharmaceutical medications. We use an organic food grade ethanol which is classified as Generally Regarded as Safe (GRAS) by the FDA as an extraction solvent. It is class 3 which means it’s a solvent that it is not known to be hazardous for humans. The other solvents people use do not meet this same standard.

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Fact-Checking: Ethanol vs CO2 Extraction

1.- Ethanol extraction requires 1/5th of the energy needed for CO2 extraction, making it much better for the environment. 2.- Our ethanol is sourced from organic agriculture, while CO2 and butane are made from toxic fossil fuels. 3.- Our extracts have all the ethanol used throughout the process removed through a distillation process, which we then get lab tested by a third party to confirm it’s completely pure before using the extract in any of the products we make. 4.- Our competitors tout using CO2 extraction because "it avoids using solvents in their process altogether." What they’re not telling you is that the process doesn’t end at CO2 extraction and what comes out of the CO2 extraction is a crude oil that needs to be further processed by being “winterized”, which involves placing it in ethanol and freezing it to remove the fats & waxes. Given supercritical CO2 extraction destroys more of the beneficial properties in the hemp plant & still requires the use of solvents, our competitors are delivering an inferior product just so they can make a vanity marketing claim.

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Benefits of CBD

Research has shown potential with the following

Frequently Asked Questions

No, it will not. Our products are non-toxic, not psychoactive, and safe to consume for your pet. CBD, the other cannabinoids, and the terpenes which comprise a majority of our formulas are non-psychoactive.

Our full spectrum products contain only trace amounts of THC (under the 0.30% legal limit) which will have no psychoactive impact on your pet and our broad spectrum products contain no THC whatsoever.

Yes, as part of the 2014 United States Farm Bill Section 7606 industrial hemp was defined as any part of the plant including the Cannabis Sativa L plant and any part or derivative of such plant, including seeds of such plant, whether growing or not, that is used for industrial purposes with a tetrahydrocannabinol (THC) concentration of not more than 0.30% on a dry weight basis. The term THC includes all isomers, acids, salts, and salts of isomers of THC. As long as the plants are sourced legally (industrial hemp grown via a state program) the extracts are legal in all 50 states and many countries around the world. All of our farming partners are registered with the state Department of Agriculture and have passed all of their inspections.

Cannabinoids are a class of compounds that act on cannabinoid receptors found throughout the body in the endocannabinoid system. Cannabinoids can be broken down into 3 main sub-classes: I. Endocannabinoids – Endocannabinoids are compounds that naturally occur in the body. A couple examples of endocannabinoids include anandamide which is known for causing runner’s high and Arachidonoylglycerol which is most known for its activities relating to brain metabolism. II. Phytocannabinoids – Phytocannabinoids are naturally occurring in plants, particularly hemp and cannabis plants. These include CBD, CBN, CBC, CBG, CBL, and THC among many others (over 100). III. Synthetic Cannabinoids – Synthetic cannabinoids are artificial and are produced in laboratories. We exclusively utilize phytocannabinoids from plants as a source for all of our products. We do not believe in synthetic sources for cannabinoids or any of the other ingredients in our products.

The first headways towards discovering the endocannabinoid system was in 1964 by when Israeli scientists Rafael Mechoulam and Yechiel Gaoni identified and isolated THC followed by CBD soon after. They knew that the cannabinoids interacted with the brain in some way but were unsure of how. Their hypothesis was confirmed in 1990 with the isolation and cloning of the first cannabinoid receptor, CB1, and later of CB2 (1993). This in addition to the discovery of the first two endocannabinoids Anandamide (1992) and Arachidonoylglycerol (1995) was how scientists worked backwards to trace THC’s metabolic pathways and map out the endocannabinoid system. Research so far has shown that the endocannabinoid system (“ECS”) plays a role in maintaining homeostasis throughout animals body’s. Through the CB1 & CB2 receptors found throughout animals body’s the ECS regulates a wide variety of high-order behavioral functions such as learning & memory, decision making, sensory and motor responsiveness, emotional reactions, and appetite. The endocannabinoid system is found in every animal except insects.

Simply put, when people mention the Entourage Effect they are talking about the interaction of different compounds when using the whole hemp plant (extracting and utilizing a majority of the plants natural compounds) vs. extracting and isolating individual compounds such as CBD and only using that. The interactions between all the cannabinoids, terpenes, and other beneficial plant matter are said to lead to additional benefits as they work together in the body.

Yes, however, we recommend consulting with a veterinarian prior to administering this and any other supplemental dietary product to your pet. Although we don’t expect there will be problems, we recommend you speak with your veterinarian before giving your pet our products if they are on other medications just to be sure. Our products should not be used if your pet is pregnant or nursing.

We suggest anywhere from 0.05mg per lb. to 0.25mg per lb. based on your pet’s total weight depending on the reasons for use. However, every pet is unique and the above should only be used as a guide.

Any of our products referred to as Broad Spectrum have the complete blend of plant material, cannabinoids, and terpenes included in our plants but contain 0.00% THC.  Any of our products with the Full Spectrum label contain the full blend of plant material, cannabinoids, and terpenes in our plants including THC but below 0.30% concentration

Tinctures / Droppers – We recommend using the dropper to squirt the suggested amounts directly into your pet’s mouth. Coconut Oil Creams & Balms – Apply locally to affected areas for targeted relief.

To maximize the quality and shelf life of your product we suggest storing our products in a dry, cool, and dark place.

All of our products are designed for maximum benefit for your pets but certain methods work faster than others. For the fastest absorption we suggest using our tinctures and administering them with the dropper directly into your pet’s mouth. If your pet needs targeted relief you can also use our topicals directly on the affected area. If you are asking about mixing our hemp oil extract with your pet's food or treats, the answer is: yes, you can. However, mixing the oil into your pet’s food or treats will mean it will be absorbed through the digestive process which takes longer than when it is ingested directly orally.

Still Have Questions? Or Just Want to Say Hello?

Please don't hesitate to reach out at hi@leafwellpets.com